Difference between revisions of "Integrating DNA strand-displacement circuitry with DNA tile self-assembly"
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|abstract=DNA tile self-assembly provides a molecular architecture for algorithmically programming the growth of complex but static geometrical structures with molecular precision. DNA strand displacement circuitry provides a molecular architecture for algorithmically programming the temporal dynamics of well-mixed solutions by design of chemical reaction pathways. What might be achieved by integrating them to enable programmable control over spatial and temporal self-organization simultaneously? Here, we use an upstream strand-displacement catalytic circuit to control the timing of a downstream tile-assembly system to isothermally grow DNA nanotubes. | |abstract=DNA tile self-assembly provides a molecular architecture for algorithmically programming the growth of complex but static geometrical structures with molecular precision. DNA strand displacement circuitry provides a molecular architecture for algorithmically programming the temporal dynamics of well-mixed solutions by design of chemical reaction pathways. What might be achieved by integrating them to enable programmable control over spatial and temporal self-organization simultaneously? Here, we use an upstream strand-displacement catalytic circuit to control the timing of a downstream tile-assembly system to isothermally grow DNA nanotubes. | ||
|authors=David Yu Zhang, Rizal F. Hariadi, Harry M. T. Choi, and Erik Winfree | |authors=David Yu Zhang, Rizal F. Hariadi, Harry M. T. Choi, and Erik Winfree | ||
− | |file=[http://www.dna.caltech.edu/Papers/CatalyzedTubes2013.pdf Integrating DNA strand-displacement circuitry with DNA tile self-assembly] | + | |file=[http://www.dna.caltech.edu/Papers/CatalyzedTubes2013.pdf Integrating DNA strand-displacement circuitry with DNA tile self-assembly.pdf] |
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Latest revision as of 13:05, 22 June 2021
Published on: 2013/06/12
Abstract
DNA tile self-assembly provides a molecular architecture for algorithmically programming the growth of complex but static geometrical structures with molecular precision. DNA strand displacement circuitry provides a molecular architecture for algorithmically programming the temporal dynamics of well-mixed solutions by design of chemical reaction pathways. What might be achieved by integrating them to enable programmable control over spatial and temporal self-organization simultaneously? Here, we use an upstream strand-displacement catalytic circuit to control the timing of a downstream tile-assembly system to isothermally grow DNA nanotubes.
Authors
David Yu Zhang, Rizal F. Hariadi, Harry M. T. Choi, and Erik Winfree
File
Integrating DNA strand-displacement circuitry with DNA tile self-assembly.pdf